Vaccines for Cancer Treatment
JAMA Clinical Reviews

Vaccines for Cancer Treatment

B2Upper-intermediateSeptember 21, 202620 min
  • Interview
  • Health

Cancer vaccines stimulate immune cells to recognize proteins or mutations found on or within cancer cells, facilitating destruction of cancer cells. Several vaccines are approved and others are in development for cancer treatment. Author Nora Disis, MD, JAMA Deputy Editor and Editor in Chief of JAMA Oncology, discusses cancer vaccines and more with JAMA Deputy Editor Mary McDermott, MD. Related Content: Vaccines for Cancer

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what is a cancer vaccine and how does it work? Well, a cancer vaccine is actually quite a complex

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is going to be trained to recognize.

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0:48

Welcome to listeners from around the world and thank you for tuning into this JAMA Clinical Review podcast. I am your host, Mary McDermott, deputy editor of JAMA, and I'm here today with Dr. Nora Deasis, who's author of a JAMA Translational Review on the topic of vaccines for cancer. Dr. Deasis is professor of medicine at the University of Washington. She is also editor

1:14

in chief of JAMA Oncology, and she is a deputy editor at JAMA. Welcome, Nora. Thank you so much for joining me today. Thank you, Mary. Let's get started. Could you start us off by telling us what is a cancer vaccine and how does it work? Well, a cancer vaccine is actually quite a complex drug. It consists of a payload, which is the immunogenic protein that the immune system's

1:44

is going to be trained to recognize. An adjuvant is the second component, which is a substance that boosts the immune system. And then the third component is kind of the delivery vehicle that delivers the adjuvant and the payload to the immune system.

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