Lab-in-the-Loop at Compute Speed — Ian Quigley, Leash Bio

A few years ago I stumbled upon Leash Bio’s Substack, and was hooked. Be it their Kaggle competition that showed that no, we really haven’t solved protein-ligand binding, or their crazy discovery that knowing a molecule’s author is perhaps all you need to know to predict how good it is. Their substack — or at least Owl Posting’s deep dive on them — should be required reading for any scientist trying to do chemistry with AI. So I was super excited to finally be able to sit down with Ian Quigley from Leash Bio, and pick his bra...